Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Developmental biology

Tethered wings

Wnt signalling molecules are thought to direct the development of an organism by spreading through tissues. But flies grow with almost normal appendages even when their main Wnt protein cannot move. Two scientists discuss the implications of this finding for our understanding of development. See Article p.180

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Wing development and Wingless spread.

References

  1. Alexandre, C., Baena-Lopez, A. & Vincent, J.-P. Nature 505, 180–185 (2014).

    Article  ADS  CAS  Google Scholar 

  2. Lawrence, P. A. & Struhl, G. Cell 85, 951–961 (1996).

    Article  CAS  Google Scholar 

  3. Zecca, M., Basler, K. & Struhl, G. Cell 87, 833–844 (1996).

    Article  CAS  Google Scholar 

  4. Nellen, D., Burke, R., Struhl, G. & Basler, K. Cell 85, 357–368 (1996).

    Article  CAS  Google Scholar 

  5. Baena-Lopez, L. A., Alexandre, C., Mitchell, A., Pasakarnis, L. & Vincent, J.-P. Development 140, 4818–4825 (2013).

    Article  CAS  Google Scholar 

  6. Zecca, M. & Struhl, G. Development 134, 3001–3010 (2007).

    Article  CAS  Google Scholar 

  7. MacDonald, B. T., Tamai, K. & He, X. Dev. Cell 17, 9–26 (2009).

    Article  CAS  Google Scholar 

  8. Neumann, C. J. & Cohen, S. M. Development 124, 871–880 (1997).

    CAS  Google Scholar 

  9. Locke, M. & Huie, P. Tissue Cell 13, 787–803 (1981).

    Article  CAS  Google Scholar 

  10. Gradilla, A.-C. & Guerrero, I. Curr. Opin. Genet. Dev. 23, 363–373 (2013).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding authors

Correspondence to Ginés Morata or Gary Struhl.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Morata, G., Struhl, G. Tethered wings. Nature 505, 162–163 (2014). https://doi.org/10.1038/nature12848

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nature12848

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing