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Stem cells

Regulation by alternative splicing

Stem-cell differentiation is controlled by RNA processing — as well as by gene expression and transcription. This finding is a milestone towards realizing these cells' potential for research and therapy. See Letter p.241

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Figure 1: Multilayer regulation of cell differentiation.


  1. *This article and the paper under discussion2 were published online on 5 June 2013.


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Correspondence to Eran Meshorer.

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Aaronson, Y., Meshorer, E. Regulation by alternative splicing. Nature 498, 176–177 (2013).

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