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The ylide has landed

The enzyme co-substrate SAM has long been known to have two chemically distinct roles. A study of the CmoA enzyme suggests that SAM has a third trick up its sleeve — it forms species known as ylides. See Letter p.123

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Figure 1: An ylide biosynthetic intermediate.


  1. *This article and the paper under discussion3 were published online on 15 May 2013.


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Correspondence to Squire J. Booker.

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Landgraf, B., Booker, S. The ylide has landed. Nature 498, 45–47 (2013).

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