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Molecular biology

Circles reshape the RNA world

The versatility of RNA seems limitless. The latest surprise comes from circular RNAs, which are found to counteract the function of another class of regulatory RNA — the microRNAs. See Article p.333 & Letter p.384

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Figure 1: Constraints on evolutionary change in microRNAs.


  1. *This article and the papers under discussion1,2 were published online on 27 February 2013.


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Correspondence to Kenneth S. Kosik.

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Kosik, K. Circles reshape the RNA world. Nature 495, 322–324 (2013).

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