A study shows that, rather than sequentially starting and stopping a movement, two parallel pathways involving neurons in the brain's basal ganglia seem to work in tandem to accomplish the complex task of motion. See Letter p.238
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Notes
*This article and the paper under discussion1 were published online on 23 January 2013.
References
Cui, G. et al. Nature 494, 238–242 (2013).
Albin, R. L., Young, A. B. & Penney, J. B. Trends Neurosci. 12, 366–375 (1989).
Mink, J. W. Prog. Neurobiol. 50, 381–425 (1996).
Hikosaka, O., Takikawa, Y. & Kawagoe, R. Physiol. Rev. 80, 953–978 (2000).
Nambu, A. Curr. Opin. Neurobiol. 18, 595–604 (2008).
Kravitz, A. V. & Kreitzer, A. C. Curr. Opin. Neurobiol. 21, 433–439 (2011).
Bateup, H. S. et al. Proc. Natl Acad. Sci. USA 107, 14845–14850 (2010).
Gerfen, C. R. & Surmeier, D. J. Annu. Rev. Neurosci. 34, 441–466 (2011).
Yasuda, M., Yamamoto, S. & Hikosaka, O. J. Neurosci. 32, 16917–16932 (2012).
Raz, A., Vaadia, E. & Bergman, H. J. Neurosci. 20, 8559–8571 (2000).
Levy, R. et al. Brain 125, 1196–1209 (2002).
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Surmeier, D. To go or not to go. Nature 494, 178–179 (2013). https://doi.org/10.1038/nature11856
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DOI: https://doi.org/10.1038/nature11856
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