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Structural biology

Antiviral drugs fit for a purpose

Did drug researchers have a lucky break when they developed antiviral drugs for influenza? Crystal structures of enzymes from the H5N1 virus suggest that they did, and provide avenues for further exploration.

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Figure 1: Induced fit of an enzyme inhibitor.

Notes

  1. *This article and the paper concerned1 were published online on 16 August 2006.

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Luo, M. Antiviral drugs fit for a purpose. Nature 443, 37–38 (2006). https://doi.org/10.1038/nature05003

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