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Calcium channel blocker-induced gingival enlargement

Journal of Human Hypertension volume 28, pages 10–14 (2014)Cite this article

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Abstract

Despite the popularity and wide acceptance of the calcium channel blockers (CCBs) by the medical community, their oral impact is rarely recognized or discussed. CCBs, as a group, have been frequently implicated as an etiologic factor for a common oral condition seen among patients seeking dental care: drug-induced gingival enlargement or overgrowth. This enlargement can be localized or generalized, and can range from mild to extremely severe, affecting patient’s appearance and function. Treatment options for these patients include cessation of the offending drug and substitution with another class of antihypertensive medication to prevent recurrence of the lesions. In addition, depending on the severity of the gingival overgrowth, nonsurgical and surgical periodontal therapy may be required. The overall objective of this article is to review the etiology and known risk factors of these lesions, their clinical manifestations and periodontal management.

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Authors and Affiliations

  1. Department of Periodontology, College of Dentistry, University of Tennessee Health Science Center, Memphis, TN, USA

    R Livada & J Shiloah

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  1. R Livada
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  2. J Shiloah
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Correspondence to R Livada.

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Livada, R., Shiloah, J. Calcium channel blocker-induced gingival enlargement. J Hum Hypertens 28, 10–14 (2014). https://doi.org/10.1038/jhh.2013.47

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  • DOI: https://doi.org/10.1038/jhh.2013.47

Keywords

  • calcium channel blockers
  • gingival enlargement
  • gingivectomy

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