Summary
In most cases with a constitutional dicentric chromosome, one of the two centromeres on each dicentric chromosome is inactivated. This is associated with the loss of Cd-positive structure although both centromeres remain C positive.
In this paper, a case of dicentric chromosome is described in which the inactivation of a centromere is, to our surprise, associated with the loss of C-positive heterochromatin.
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Nakagome, Y., Nakahori, Y., Mitani, K. et al. The loss of centromeric heterochromatin from an inactivated centromere of a dicentric chromosome. Jap J Human Genet 31, 21–26 (1986). https://doi.org/10.1007/BF01876798
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DOI: https://doi.org/10.1007/BF01876798
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