Abstract
Four new compounds were isolated from a marine-derived fungus Penicillium terrestre, namely 2-(2′, 3′-dihydrosorbyl)-3,6-dimethyl-5-hydroxy-1,4-benzoquinone (1), 3-acetonyl-2,6-dimethyl-5-hydroxy-1,4-benzoquinone (2), dihydrobisvertinolone (3), tetrahydrobisvertinolone (4). Their structures were established on the basis of spectroscopic methods. The absolute configurations of 3 and 4 were determined by their CD spectra. Their cytotoxic effects on P388 and A-549 cell lines were preliminarily examined by the MTT method.
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Liu, W., Gu, Q., Zhu, W. et al. Two New Benzoquinone Derivatives and Two New Bisorbicillinoids were Isolated from a Marine-derived Fungus Penicillium terrestre. J Antibiot 58, 441–446 (2005). https://doi.org/10.1038/ja.2005.57
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DOI: https://doi.org/10.1038/ja.2005.57
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