Abstract
We describe the case of a 44-year-old woman who presented with renovascular hypertension caused by primary leiomyosarcoma of the abdominal aorta that had metastasized into the renal arteries. Despite an extensive radiological evaluation, the diagnosis was mistaken first for Takayasu's arteritis and then for retroperitoneal hematoma or neoplasm. The patient developed renal failure due to bilateral renal infarction, and died 3 months after her initial presentation with ischemic colitis. Postmortem examination confirmed the diagnosis.
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Varela-Duran J, Oliva H, Rosai J : Vascular leiomyosarcoma: the malignant counterpart of vascular leiomyoma. Cancer 1979; 44: 1684–1691.
Kwon TW, Sung KB, Cho YP, et al: Pararenal leiomyosarcoma of the inferior vena cava. J Korean Med Sci 2003; 18: 355–359.
Griffin AS, Sterchi JM : Primary leiomyosarcoma of the inferior vena cava: a case report and review of the literature. J Surg Oncol 1987; 34: 53–60.
Hollenbeck ST, Grobmyer SR, Kent KC, Brennan MF : Surgical treatment and outcomes of patients with primary inferior vena cava leiomyosarcoma. J Am Coll Surg 2003; 197: 575–579.
Malone MD, Kerr K, Kavanah M, Menzoian JO : Primary leiomyosarcoma of the abdominal aorta. J Vasc Surg 1996; 24: 487–493.
Chiche L, Mongredien B, Brocheriou I, Kieffer E : Primary tumors of the thoracoabdominal aorta: surgical treatment of 5 patients and review of the literature. Ann Vasc Surg 2003; 17: 354–364.
Hartman DS, Hayes WS, Choyke PL, Tibbetts GP : From the archives of the AFIP. Leiomyosarcoma of the retroperitoneum and inferior vena cava: radiologic-pathologic correlation. Radiographics 1992; 12: 1203–1220.
Cantwell CP, Stack J : Abdominal aortic invasion by leiomyosarcoma. Abdom Imaging 2006; 31: 120–122.
Szekely E, Kulka J, Miklos I, Kaliszky P : Leiomyosarcomas of great vessels. Pathol Oncol Res 2000; 6: 233–236.
Higgins R, Posner MC, Moosa HH, Staley C, Pataki KI, Mendelow H : Mesenteric infarction secondary to tumor emboli from primary aortic sarcoma. Guidelines for diagnosis and management. Cancer 1991; 68: 1622–1627.
Pompilio G, Tartara P, Varesi C, Biglioli P : Intimal-type primary sarcoma of the thoracic aorta: an unusual case presenting with left arm embolization. Eur J Cardiothorac Surg 2002; 21: 574–576.
Burke AP, Virmani R : Sarcomas of the great vessels. A clinicopathologic study. Cancer 1993; 71: 1761–1773.
Parra JR, Perler BA : Takayasu's disease. Semin Vasc Surg 2003; 16: 200–208.
Ando K, Takahashi K, Shibata S, et al: Two cases of renovascular hypertension and ischemic renal dysfunction: reliable choice of examinations and treatments. Hypertens Res 2004; 27: 985–992.
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Iguchi, S., Alchi, B., Asakawa, K. et al. Leiomyosarcoma of the Abdominal Aorta: A Rare Cause of Renovascular Hypertension. Hypertens Res 30, 279–283 (2007). https://doi.org/10.1291/hypres.30.279
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DOI: https://doi.org/10.1291/hypres.30.279