Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Europe spent €600 million to recreate the human brain in a computer. How did it go?

A 3D-Polarized Light Image is a computing-intensive method to map the brain’s fibre architecture in microscopic resolution.

Digital reconstruction of a circuit of neurons from the temporal lobe of a human brain. Credit: Nicolas Antille

Access options

Rent or buy this article

Prices vary by article type

from$1.95

to$39.95

Prices may be subject to local taxes which are calculated during checkout

Nature 620, 718-720 (2023)

doi: https://doi.org/10.1038/d41586-023-02600-x

Updates & Corrections

  • Correction 22 August 2023: An earlier version of this News feature gave the wrong credits for the image of the digital reconstruction of a neuronal circuit and the polarized-light image of the brain.

References

  1. Amunts, K. et al. Science 369, 988–992 (2020).

    Article  PubMed  Google Scholar 

  2. Chen, X. et al. Science 370, 1191–1196 (2020).

    Article  PubMed  Google Scholar 

  3. Wang, H. E. et al. Sci. Transl. Med. 15, eabp8982 (2023).

    Article  PubMed  Google Scholar 

  4. Ruland, S. et al. Cortex 153, 235–256 (2022).

    Article  PubMed  Google Scholar 

  5. Bludau, S. et al. Am. J. Psychiatry 173, 291–298 (2016).

    Article  PubMed  Google Scholar 

  6. Gandolfi, D. et al. Nature Comput. Sci. 3, 264–276 (2023).

    Article  Google Scholar 

  7. Meier, J. M. et al. Exp. Neurol. 354, 114111 (2022).

    Article  PubMed  Google Scholar 

  8. Yin, B. et al. Nature Mach. Intell. 5, 518–527 (2023).

    Article  Google Scholar 

Download references

Subjects

Latest on:

Nature Careers

Jobs

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing

Search

Quick links