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  • RESEARCH HIGHLIGHT

Quirks of kids’ cancers are revealed — and could shape hunt for drugs

Paediatric tumours have different mutations from adults’, suggesting that some adult therapies will miss the mark in youngsters.
Coloured scanning electron micrograph of neuroblastoma cancer cells

Cells (artificially coloured) of neuroblastoma, one of the most common cancers in very young children. Credit: Eye of Science/Science Photo Library

By performing genome-scale screening in 13 types of childhood tumour, scientists have uncovered clues to the tumours’ potential Achilles heels — but have also learnt that paediatric cancers have unique vulnerabilities not present in adult tumours.

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Nature 592, 169 (2021)

doi: https://doi.org/10.1038/d41586-021-00826-1

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