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  • RESEARCH HIGHLIGHT

CRISPR helps to rid mice of HIV

Gene-editing tool joins forces with antiretroviral drugs to drive HIV from its sanctuaries.
Fig. 4, panel showing the spleen of HIV-infected mice treated with CRISPR

Immune cells (brown) called CD4+ T cells are scarcer in the spleen of an untreated HIV-infected mouse (left) than in that of a mouse treated with antiretrovirals and CRISPR gene editing (right). Credit: Kamel Khalili

A regimen that includes CRISPR gene editing has eliminated HIV from the bodies of mice infected with the virus.

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Nature 571, 148 (2019)

doi: https://doi.org/10.1038/d41586-019-02076-8

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