Abstract
Question: In patients who need oral surgery is it necessary to stop low-dose aspirin prior to treatment?
Objective To assess the effect of low-dose aspirin on intra- and post-operative bleeding during oral surgery.
Design Randomised controlled trial (RCT).
Intervention Thirty-nine patients requiring oral surgery were randomised either to a control group where low-dose aspirin was stopped 7 days prior to treatment or to a test group where aspirin therapy was continued.
Outcome measures Bleeding-time test, intra-operative bleeding.
Results In 33 out of the 39 patients, intra-operative bleeding was controlled with sutures and local pressure with gauze. The other six patients (see Table 1) had tranexaminc acid added to the local packing to control bleeding. No postoperative bleeding or other complications were reported at 1 week.
Conclusion The study suggests that there is no need to stop low-dose aspirin therapy for dental extractions and risk thromboembolic, cerebrovascular or myocardial complications.
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References
Tierney, L. M. J., McPhee, SJ, Papadakis, MA (eds) 2001). Current Medical Diagnosis and Treatment 40th edn McGraw-Hill: New York p548
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Address for reprints: L Ardekian, Department of Oral and Maxillofacial Surgery, Rambam Medical Centre, Haifa, Israel.
Ardekian L, Gaspar R, Peled M, Brener B, Laufer D. Does low-dose aspirin therapy complicate oral surgical procedures? JADA 2000; 131:331–335
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Yeo, J. No need to stop low-dose aspirin therapy prior to oral surgery. Evid Based Dent 3, 66 (2002). https://doi.org/10.1038/sj.ebd.6400122
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DOI: https://doi.org/10.1038/sj.ebd.6400122