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Drug discovery

Time in a bottle

A biological clock synchronizes animal behaviour and physiology with Earth's 24-hour rotation. Drugs targeting the clock's 'gears' show promise for treating obesity and other metabolic disorders. See Article p.62 & Letter p.123

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Correspondence to Joseph Bass.

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Competing interests

Joseph Bass provides consulting and speakers bureau services to Merck and to Gerhson Lehrman Group. He has received research funding from Amylin Pharmaceuticals, Eli Lilly and Takeda Pharmaceuticals. He is a member of the advisory board and a stockholder of Reset Therapeutics. Neither of these companies is mentioned, or specifically alluded to, in this article.

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Bass, J. Time in a bottle. Nature 485, 45–46 (2012).

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