Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Microbiology

Dicing defence in bacteria

A newly discovered variation in the process by which bacteria resist invasion by foreign nucleic acids provides an intriguing parallel between the defence mechanisms of the different domains of life. See Article p.602

This is a preview of subscription content, access via your institution

Access options

Buy article

Get time limited or full article access on ReadCube.

$32.00

All prices are NET prices.

Figure 1: Flexibility in CRISPR processing systems.

References

  1. Jaskiewicz, L. & Filipowicz, W. Curr. Top. Microbiol. Immunol. 320, 77–97 (2008).

    CAS  PubMed  Google Scholar 

  2. Deltcheva, E. et al. Nature 471, 602–607 (2011).

    ADS  CAS  Article  Google Scholar 

  3. Karginov, F. V. & Hannon, G. J. Mol. Cell 37, 7–19 (2010).

    CAS  Article  Google Scholar 

  4. Marraffini, L. A. & Sontheimer, E. J. Nature Rev. Genet. 11, 181–190 (2010).

    CAS  Article  Google Scholar 

  5. Marraffini, L. A. & Sontheimer, E. J. Science 322, 1843–1845 (2008).

    ADS  CAS  Article  Google Scholar 

  6. Hale, C. R. et al. Cell 139, 945–956 (2009).

    CAS  Article  Google Scholar 

  7. Haft, D. H., Selengut, J., Mongodin, E. F. & Nelson, K. E. PLoS Comput. Biol. 1, e60 (2005).

    ADS  Article  Google Scholar 

  8. Brouns, S. J. J. et al. Science 321, 960–964 (2008).

    ADS  CAS  Article  Google Scholar 

  9. Carte, J., Wang, R., Li, H., Terns, R. M. & Terns, M. P. Genes Dev. 22, 3489–3496 (2008).

    CAS  Article  Google Scholar 

  10. Haurwitz, R. E. et al. Science 329, 1355–1358 (2010).

    ADS  CAS  Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Susan Gottesman.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Gottesman, S. Dicing defence in bacteria. Nature 471, 588–589 (2011). https://doi.org/10.1038/471588a

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/471588a

Further reading

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing