Tumour viruses can cause cancer by altering gene expression and protein activity in the host cell. Tumour adenoviruses, however, seem to go to great lengths to ensure that one particular host cell protein, p53, is suppressed.
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References
Howley, P. M. & Livingston, D. M. Virology 384, 256–259 (2009).
Soria, C., Estermann, F. E., Espantman, K. C. & O'Shea, C. C. Nature 466, 1076–1081 (2010).
Frisch, S. M. & Mymryk, J. S. Nature Rev. Mol. Cell Biol. 3, 441–452 (2002).
Helgason, G. V., O'Prey, J. & Ryan, K. M. Cancer Res. 70, 4074–4080 (2010).
Sherr, C. J. & McCormick, F. Cancer Cell 2, 103–112 (2002).
Berk, A. J. Oncogene 24, 7673–7685 (2005).
Hemann, M. T. et al. Nature Genet. 33, 396–400 (2003).
Bensaad, K. et al. Cell 126, 107–120 (2006).
O'Shea, C. C. Oncogene 24, 7640–7655 (2005).
O'Shea, C. C. et al. Cancer Cell 6, 611–623 (2004).
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Ryan, K. Viruses' backup plan. Nature 466, 1054–1055 (2010). https://doi.org/10.1038/4661054a
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DOI: https://doi.org/10.1038/4661054a