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The structure of the Escherichia coli EF-Tu· EF-Ts complex at 2.5 Å resolution

A Correction to this article was published on 09 May 1996


The crystal structure of the EF-Tu·EF-Ts complex from Escherichia coli has been determined to a resolution of 2.5 Å. The complex contains two subunits of each of the elongation factors. The two EF-Ts molecules form a tight dirtier, but there is little contact between the two EF-Tu molecules. The interaction of EF-Ts with EF-Tu results principally in the disruption of the Mg2+ ion binding site, thereby reducing the affinity of EF-Tu for guanine nucleotides.

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Kawashima, T., Berthet-Colominas, C., Wulff, M. et al. The structure of the Escherichia coli EF-Tu· EF-Ts complex at 2.5 Å resolution. Nature 379, 511–518 (1996).

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