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Green chemistry

Designed to dissolve

Many solvents are unpleasant but essential industrial chemicals. Supercritical carbon dioxide would be a viable ‘green’ alternative but its use has been restricted by its limited solvent power. This is about to change.

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Figure 1: Phase diagram for carbon dioxide.
Figure 2: The design of CO2-philic materials.


  1. McHugh, M. & Krukonis, V. J. Supercritical Fluid Extraction 2nd edn (Butterworth-Heinemann, Boston, 1994).

    Google Scholar 

  2. Jessop, P. G. & Leitner, W. (eds) Chemical Synthesis Using Supercritical Fluids (Wiley-VCH, Weinheim, 1999).

    Book  Google Scholar 

  3. Noyori, R. (guest ed.) Chem. Rev. 99, issue 2 ( 1999).

  4. Sarbu, T., Styranec, T. & Beckman, E. J. Nature 405, 165– 168 (2000).

    Article  ADS  CAS  Google Scholar 

  5. Zosel, K. Angew. Chem. Int. Edn Engl. 17, 702– 709 (1978).

    Article  Google Scholar 

  6. DeSimone, J. M. et al. Science 265, 356–359 (1994).

    Article  ADS  CAS  Google Scholar 

  7. Johnston, K. P. et al. Science 271, 624–626 (1996).

    Article  ADS  CAS  Google Scholar 

  8. Laintz, K. E., Wai, C. M., Yonker, C. R. & Smith, R. D. Anal. Chem. 64, 2875–2878 (1992).

    Article  CAS  Google Scholar 

  9. Kainz, S., Koch, D., Baumann, W. & Leitner, W. Angew. Chem. Int. Edn Engl. 36, 1628–1630 (1997).

    Article  CAS  Google Scholar 

  10. Hadida, S., Super, M. S., Beckman, E. J. & Curran, D. P. J. Am. Chem. Soc. 119, 7406–7407 (1997).

    Article  CAS  Google Scholar 

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Correspondence to Walter Leitner.

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Leitner, W. Designed to dissolve. Nature 405, 129–130 (2000).

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