Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Article
  • Published:

Requirement of stereospecific alignments for initiation from the simian virus 40 early promoter

Nature volume 319, pages 121–126 (1986)Cite this article

Abstract

The distance between the simian virus 40 early promoter elements has been altered by inserting either odd or even multiples of half a DNA turn. There are marked differences in the in vivo effects of these two types of insertions on initiation of transcription from this promoter.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Wasylyk, B., Wasylyk, C., Matthes, H., Wintzerith, M. & Chambon, P. EMBO J. 2, 1605–1611 (1983).

    Article  CAS  Google Scholar 

  2. Vigneron, M., Barrera-Saldana, H. A., Baty, D., Everett, R. E. & Chambon, P. EMBO J. 3, 2373–2382(1984).

    Article  CAS  Google Scholar 

  3. Buchman, A. R., Fromm, M. & Berg, P. Molec. cell. Biol. 4, 1900–1914 (1984).

    Article  CAS  Google Scholar 

  4. Barrera-Saldana, H. A. et al. EMBO J. (in the press).

  5. Baty, D., Barrera-Saldana, H. A., Everett, R. D., Vigneron, M. & Chambon, P. Nucleic Acids Res. 12, 915–932 (1984).

    Article  CAS  Google Scholar 

  6. Zenke, M. et al. EMBO J. (in the press).

  7. Davison, B. L., Egly, J. M., Mulvihill, E. R. & Chambon, P. Nature 301, 680–686 (1983).

    Article  ADS  CAS  Google Scholar 

  8. Parker, C. S. & Topol, J. Cell 37, 273–283 (1984).

    Article  CAS  Google Scholar 

  9. Dynan, W. S. & Tjian, R. Cell 32, 669–680 (1983).

    Article  CAS  Google Scholar 

  10. Dynan, W. S. & Tjian, R. Cell 35, 79–87 (1983).

    Article  CAS  Google Scholar 

  11. Gidoni, D., Dynan, W. S. & Tjian, R. Nature 312, 409–413 (1984).

    Article  ADS  CAS  Google Scholar 

  12. Sassone-Corsi, P., Dougherty, J. P., Wasylyk, B. & Chambon, P. Proc. natn. Acad. Sci. U.S.A. 81, 308–312 (1984).

    Article  ADS  CAS  Google Scholar 

  13. Sassone-Corsi, P., Wildeman, A. G. & Chambon, P. Nature 313, 458–463 (1985).

    Article  ADS  CAS  Google Scholar 

  14. Wildeman, A. G., Sassone-Corsi, P., Grundström, T., Zenke, M. & Chambon, P. EMBO J. 3, 3129–3133(1984).

    Article  CAS  Google Scholar 

  15. Sergeant, A., Bohmann, D., Zentgraf, H., Weiher, H. & Keller, W. J. molec. Biol. 180, 577–600 (1984).

    Article  CAS  Google Scholar 

  16. Wildeman, A. G. et al. Molec. cell. Biol. (submitted).

  17. Moreau, P. et al. Nucleic Acids Res. 9, 6047–6068 (1981).

    Article  ADS  CAS  Google Scholar 

  18. Banerji, J., Rusconi, S. & Schaffner, W. Cell 27, 299–308 (1981).

    Article  CAS  Google Scholar 

  19. Wasylyk, B., Wasylyk, C. & Chambon, P. Nucleic Acids Res. 12, 5589–5608 (1984).

    Article  CAS  Google Scholar 

  20. Wang, J. Proc. natn. Acad. Sci. U.S.A. 76, 200–203 (1979).

    Article  ADS  CAS  Google Scholar 

  21. Everett, R. D., Baty, D. & Chambon, P. Nucleic Acids Res. 11, 2447–2464 (1983).

    Article  CAS  Google Scholar 

  22. Hansen, U. & Sharp, P.A. EMBO J. 2, 2293–2303 (1983).

    Article  CAS  Google Scholar 

  23. Miyamoto, N. G., Moncollin, V., Egly, J. M. & Chambon, P. Nucleic Acids Res. 12, 8779–8799 (1984).

    Article  CAS  Google Scholar 

  24. Wasylyk, B., Wasylyk, C., Augereau, P. & Chambon, P. Cell 32, 503–514 (1983).

    Article  CAS  Google Scholar 

  25. Hochschild, A., Irwin, N. & Ptashne, M. Cell 32, 319–325 (1983).

    Article  CAS  Google Scholar 

  26. Wharton, R. P., Brown, E. L. & Ptashne, M. Cell 38, 361–369 (1984).

    Article  CAS  Google Scholar 

  27. Ptashne, M. Trends biochem. Sci. 9, 142–145 (1984).

    Article  Google Scholar 

  28. Kedinger, C., Gissinger, F. & Chambon, P. Eur. J. Biochem. 44, 421–436 (1974).

    Article  CAS  Google Scholar 

  29. Tooze, J.(ed.) DNA Tumor Viruses (Cold Spring Harbor Laboratory, New York, 1982).

  30. Matthes, H. W. D. et al. EMBO J. 3, 801–805 (1984).

    Article  CAS  Google Scholar 

  31. Grundström, T. et al. Nucleic Acids Res. 13, 3305–3316 (1985).

    Article  Google Scholar 

  32. Wallace, R. B. et al. Gene 16, 21–38 (1981).

    Article  CAS  Google Scholar 

Download references

Author information

Author notes

  1. Keikichi Takahashi

    Present address: Medical Institute for Bioregulation, Kyushu University, Maedashi 3-1-1, Higashi-ku, Fukuoka, 812, Japan

  2. Marc Vigneron

    Present address: Department of Virology, The Weizmann Institute for Science, Rehovot, Israel

  3. Alan Wildeman

    Present address: Department of Molecular Biology and Genetics, University of Guelph, Guelph, Ontario, Canada, NIG 2W1

  4. M. Zenke

    Present address: European Molecular Biology Laboratory, Postfach 102209, D-6900, Heidelberg, FRG

Authors and Affiliations

  1. Laboratoire de Génétique Moléculaire des Eucaryotes, CNRS, Unité 184 de Biologie Moléculaire et de Génie Génétique, INSERM, Institut de Chimie Biologique, Faculté de Médecine, Strasbourg, 67085 Cédex, France

    Keikichi Takahashi, Marc Vigneron, Hans Matthes, Alan Wildeman, M. Zenke & Pierre Chambon

Authors
  1. Keikichi Takahashi
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Marc Vigneron
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Hans Matthes
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Alan Wildeman
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. M. Zenke
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Pierre Chambon
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Takahashi, K., Vigneron, M., Matthes, H. et al. Requirement of stereospecific alignments for initiation from the simian virus 40 early promoter. Nature 319, 121–126 (1986). https://doi.org/10.1038/319121a0

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1038/319121a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing