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Effects of oxotremorine demonstrate presynaptic muscarinic and dopaminergic receptors on motor nerve terminals

Abstract

THERE has been little conclusive evidence about the presynaptic effects of acetylcholine (ACh) and cholinomimetics on mammalian motor nerve terminals1,2 which may have functional implications in motor abnormalities3,4. We now report the existence of dopaminoceptive muscarinic receptors on motor nerve terminals which participate in the local release of ACh from motor nerve terminals.

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GANGULY, D., DAS, M. Effects of oxotremorine demonstrate presynaptic muscarinic and dopaminergic receptors on motor nerve terminals. Nature 278, 645–646 (1979). https://doi.org/10.1038/278645a0

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