Abstract
THE transplantation of embryonic eyes in Amphibia is a long established approach for testing the ability of nerve fibres to grow through unusual regions of the central nervous system1,2. As the behaviour of growing ectopic fibres may disclose the mechanisms of axonal guidance3–7, this approach has recently attracted new interest8–12. We are studying the behaviour of optic fibres entering the spinal cord from a heterotopic eye grafted on to the dorsal trunk region of Xenopus embryos10,11. Here we report on the paths used by ectopic fibres to travel in the spinal cord, their possible termination in the hindbrain, and their ability to reach the optic tectum.
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GIORGI, P., VAN DER LOOS, H. Axons from eyes grafted in Xenopus can grow into the spinal cord and reach the optic tectum. Nature 275, 746–748 (1978). https://doi.org/10.1038/275746a0
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DOI: https://doi.org/10.1038/275746a0
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