Letter | Published:

Distribution of butanol molecules along bullfrog olfactory mucosa


ALTHOUGH electrophysiological1 and gas chromatographic2 studies have indicated that odorant molecules drawn into the intact frog olfactory sac establish a concentration gradient along the olfactory mucosa, conclusive evidence for such gradients requires a direct determination of how the molecules are actually distributed. This requirement is met here by labelling butanol molecules with tritium and directly mapping their sorption along the mucosa.

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  1. 1

    Mozell, M. M., J. gen. Physiol., 50, 25–41 (1966); ibid, 56, 46–63 (1970).

  2. 2

    Mozell, M. M., and Jagodowicz, M., Science, 181, 1247–1249 (1973), Ann. N. Y. Acad. Sci., 237, 76–90 (1974).

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