Abstract
WHEN oestrogen molecules enter a target cell they are bound by specific receptors in the cytoplasm which then enter the nucleus carrying the hormone1. In the nucleus the hormone-receptor complexes bind to acceptor sites, where they presumably initiate the sequence of events comprising the hormone response.
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CHAMNESS, G., JENNINGS, A. & MCGUIRE, W. Oestrogen Receptor Binding is not restricted to Target Nuclei. Nature 241, 458–460 (1973). https://doi.org/10.1038/241458a0
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DOI: https://doi.org/10.1038/241458a0
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