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Cigarette Smoke: Effect of Aqueous and Nonaqueous Fractions on Mitochondrial Function

Nature volume 241, pages 287–288 (1973)Cite this article

Abstract

TOBACCO smoke or components exert inhibitory effects on respiratory cilia1 and the ciliary activity of Paramecium2–4. Kennedy and Elliot5 observed that in Tetrahymena tobacco smoke caused structural alteration in the inner mitochondrial membrane followed by the cessation of ciliary activity, attributed to a block in the energy generation process in mitochondria. Because the latter are the primary sites of energy production in an aerobic cell, we studied the effects of tobacco smoke components on mitochondrial function. Effects of aqueous and nonaqueous fractions from whole smoke of tobacco on mitochondrial respiration and coupled energy generation were examined.

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References

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Authors and Affiliations

  1. School of Biological Sciences, University of Kentucky, Lexington, Kentucky, 40506

    C. GAIROLA & M. I. H. ALEEM

Authors
  1. C. GAIROLA
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  2. M. I. H. ALEEM
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GAIROLA, C., ALEEM, M. Cigarette Smoke: Effect of Aqueous and Nonaqueous Fractions on Mitochondrial Function. Nature 241, 287–288 (1973). https://doi.org/10.1038/241287a0

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