Letter | Published:

Quinacrine Mustard Fluorescence of Sex Chromatin in Human Amniotic Fluid Cell Cultures


SINCE the work of Zech1, a fluorescent staining technique has been used for identification of the Y chromosome in the interphase nuclei of cells from human male subjects. No recognizable fluorescence of the Barr body or sex chromatin mass has been observed in the nuclei of uncultured human amniotic fluid cells from female foetuses obtained by amniocentesis.

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