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Influence of an Adrenergic Potentiator on the Ocular Response to Catecholamines in Primates and Man

Abstract

THE part played by adrenergic receptors in the regulation of intraocular pressure has been considerably clarified as a result of recent anatomical, physiological and pharmacological studies. A significant decrease in the rate of formation of the aqueous humour which results in a lowered equilibrium pressure in the eye can be brought about by electrical stimulation of the preganglionic cervical sympathetic nerve1. Pharmacologically, a decrease in the inflow of aqueous humour in animals and man follows the topical administration of l-adrenaline and l-isoprenaline2,3, and a decrease in the resistance to outflow of the aqueous humour in animal eyes can be induced by l-noradrenaline2.

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References

  1. Langham, M. E., and Rosenthal, A. R., Amer. J. Physiol., 210, 786 (1966).

    CAS  PubMed  Google Scholar 

  2. Eakins, K. E., J. Pharmacol. Exp. Ther., 140, 79 (1963).

    CAS  Google Scholar 

  3. Weekers, R., Delmarcelle, Y., and Gustin, J., Amer. J. Ophthalmol., 40, 666 (1955).

    Article  CAS  Google Scholar 

  4. Langham, M. E., and Carmel, D. D., J. Pharmacol. Exp. Ther. (in the press).

  5. Sigg, E. B., Soffer, L., and Gyermek, L., J. Pharmacol. Exp. Ther., 142, 13 (1963).

    CAS  PubMed  Google Scholar 

  6. Stone, C. A., Porter, C. C., Stocvorski, J. M., Ludden, C. T., and Totaro, J. A., J. Pharmacol. Exp. Ther., 144, 196 (1964).

    CAS  PubMed  Google Scholar 

  7. Malmfors, T., Acta Physiol. Scand., 65, 259 (1965).

    Article  CAS  Google Scholar 

  8. Langham, M. E., and Taylor, C. B., J. Physiol., 152, 437 (1960).

    Article  CAS  Google Scholar 

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KITAZAWA, Y., LANGHAM, M. Influence of an Adrenergic Potentiator on the Ocular Response to Catecholamines in Primates and Man. Nature 219, 1376–1378 (1968). https://doi.org/10.1038/2191376a0

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