Article

Reconstruction of Three Dimensional Structures from Electron Micrographs

  • Nature volume 217, pages 130134 (13 January 1968)
  • doi:10.1038/217130a0
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Abstract

General principles are formulated for the objective reconstruction of a three dimensional object from a set of electron microscope images. These principles are applied to the calculation of a three dimensional density map of the tail of bacteriophage T4.

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Affiliations

  1. MRC Laboratory of Molecular Biology, Hills Road, Cambridge

    • D. J. DE ROSIER
    •  & A. KLUG

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