Actions of Thrombin and Other Coagulant and Proteolytic Enzymes on Blood Platelets


The action of thrombin on fibrinogen is not responsible for its effect on platelets. Thrombin does, however, have an enzyme effect on a platelet constituent: this requires an unsubstituted serine hydroxyl group and a group susceptible to acetylation.

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DAVEY, M., LÜSCHER, E. Actions of Thrombin and Other Coagulant and Proteolytic Enzymes on Blood Platelets. Nature 216, 857–858 (1967).

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