Abstract
AT present there is no adequate therapy for human diseases of immunological deficiency. Immunological reconstitution of children suffering from congenital thymic dysplasia has been attempted using allogeneic lymphoid tissues from pre- or postnatal donors, but these efforts remained unsuccessful1,2, or were followed by a fatal reaction of the graft against the host3.
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References
Rosen, F. S., Gotoff, S. P., Craig, J. M., Ritchie, J., and Janeway, C. A., New Engl. J. Med., 274, 18 (1966).
Hitzig, W. H., Kay, H. E. M., and Cottier, H., Lancet, ii, 151 (1965).
Miller, M. E., J. Pediatrics, 70, 730 (1967).
Miller, J. F. A. P., Ann. NY Acad. Sci., 99, 340 (1962).
Hilgard, H. R., Yunis, E. J., Sjodin, K., Martinez, C., and Good, R. A., Nature, 202, 668 (1964).
Yunis, E. J., Hilgard, H. R., Martinez, C., and Good, R. A., J. Exp Med., 121, 607 (1965).
Uphoff, D. E., Proc. Soc. Exp. Biol. and Med., 99, 651 (1958).
Schwartz, R. S., and Beldotti, L., Transplantation, 3, 79 (1965).
Foker, J. E., McKneally, M. F., and Michael, A. F., Fed. Proc. Abst. (1967).
Iyer, V. N., and Szybalski, W., Proc. US Nat. Acad. Sci., 50, 355 (1963).
Caspersson, T., Farber, S., Foley, G. E., Killander, D., and Zetterberg, A., Exp. Cell Res., 39, 365 (1965).
Bloom, B. R., Hamilton, L. D., and Chase, M. W., Nature, 201, 689 (1964).
Simonsen, M., Engelbreth-Holm, J., Jensen, E., and Poulsen, H., Ann. NY Acad. Sci., 73, 834 (1958).
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MEUWISSEN, H., GOOD, R. Suppression of Graft versus Host Reaction by Mitomycin C. Nature 215, 634–635 (1967). https://doi.org/10.1038/215634a0
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DOI: https://doi.org/10.1038/215634a0
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