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Haemoglobin Sydney: β67 (EII) Valine→ Alanine : an Emerging Pattern of Unstable Haemoglobins

Nature volume 215, pages 626–628 (1967)Cite this article

Abstract

SEVERAL abnormal haemoglobins have recently been found in patients with inclusion body haemolytic anaemias1, and have been called unstable because they form precipitates more readily than haemoglobin A when warmed to 50° C. We now report the identification of the structural abnormality in one of these haemoglobins—haemoglobin Sydney—the haematology and the family study of which have already been described2.

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Authors and Affiliations

  1. MRC Abnormal Haemoglobin Research Unit, University Department of Biochemistry, Cambridge

    R. W. CARRELL, H. LEHMANN & P. A. LORKIN

  2. Kanematsu Memorial Institute, Sydney Hospital, Sydney

    EVA RAIK & ELIZABETH HUNTER

Authors
  1. R. W. CARRELL
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  2. H. LEHMANN
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  3. P. A. LORKIN
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  4. EVA RAIK
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  5. ELIZABETH HUNTER
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CARRELL, R., LEHMANN, H., LORKIN, P. et al. Haemoglobin Sydney: β67 (EII) Valine→ Alanine : an Emerging Pattern of Unstable Haemoglobins. Nature 215, 626–628 (1967). https://doi.org/10.1038/215626a0

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