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Cause of Homologous Disease

Naturevolume 214pages2629 (1967) | Download Citation

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Abstract

When hybrid mice are injected with spleen cells from one of the parent strains, they develop symptoms leading to death. Animals dying from this “homologous disease” frequently have enlarged adrenal glands. The possibility that this disease results from adrenal hyperactivity is explored by investigating two of its features—thymic involution and reactions of peripheral lymphoid tissue.

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Affiliations

  1. Departments of Microbiology and Physiology, and Pediatric Research Laboratories of the Variety Club Heart Hospital, University of Minnesota

    • LYLE R. HEIM
    • , CARLOS MARTINEZ
    •  & ROBERT A. GOOD

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https://doi.org/10.1038/214026a0

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