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Specific Antigenicity of Thymocytes

Nature volume 213, pages 1135–1136 (1967)Cite this article

Abstract

THYMOCYTES (thymic lymphocytes) are believed to differ from lymphoid cells of other organs. They show a different response to a variety of physical, chemical and biological stimuli1, such as irradiation2 and phytohaemagglutinin3, and it has been claimed that they have an epithelial rather than mesenchymal origin4. In the mouse, autoantibodies5 and isoantibodies6,7 have been demonstrated with a selective toxic effect on thymocytes. The present investigation with a heterologous thymus-specific antiserum reveals rat thymocytes differing antigenically from the lymphoid cells of lymphatic circulation, lymph node and spleen.

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Authors and Affiliations

  1. Department of Pathology, Monash University, Melbourne

    E. F. POTWOROWSKI & R. C. NAIRN

Authors
  1. E. F. POTWOROWSKI
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  2. R. C. NAIRN
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POTWOROWSKI, E., NAIRN, R. Specific Antigenicity of Thymocytes. Nature 213, 1135–1136 (1967). https://doi.org/10.1038/2131135b0

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