Abstract
ALTHOUGH the number of chromosomes in the diploid set varies from seventeen to eighty, placental mammals as a whole comprise one uniform group with regard to total genetic content1–3. Diverse speciation from the common ancestor, protoinseetivores, was apparently accomplished by re-arrangement of linkage groups and mutations of individual genes. The X-chromosome, however, appears to have escaped rearrangement. The X-chromosomes of a great majority of placental mammals, including man, cattle, the mouse, the dog, the horse, and the donkey, have been found to be almost identical in absolute size, comprising about 5 per cent of the genome4. This suggests that the primitive X-chromosome of proto-insectivores has persisted in its entirety in various placental mammals.
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MATHAI, C., OHNO, S. & BEUTLER, E. Sex-linkage of the Glucose-6-phosphate Dehydrogenase Gene in Equidae. Nature 210, 115–116 (1966). https://doi.org/10.1038/210115a0
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DOI: https://doi.org/10.1038/210115a0
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