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Isolation of a Pre-viral Deoxyribonucleic Acid

Nature volume 210, pages 1158–1159 (1966)Cite this article

Abstract

IN 1943, we found that hydroxylamine can induce viral polyhedrosis in silkworms1. Pursuing this finding, one of us has established a metabolic cycle producing virogens and mutagens2. It has further been demonstrated that the polyhedral pre-viral genome is located in the chromosome of the host cell3. We have now succeeded in isolating the pre-viral deoxyribonucleic acid from the larval nucleus and have confirmed that hydroxylamine is able to accelerate its separation from the other nucleic acid portion.

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Authors and Affiliations

  1. Agricultural Chemistry Institute and Food Science Institute, Kyushu University, Fukuoka, Japan

    KAZUO YAMAFUJI & FUMIO HASHINAGA

Authors
  1. KAZUO YAMAFUJI
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  2. FUMIO HASHINAGA
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YAMAFUJI, K., HASHINAGA, F. Isolation of a Pre-viral Deoxyribonucleic Acid. Nature 210, 1158–1159 (1966). https://doi.org/10.1038/2101158a0

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