Abstract
THE cause of renal stone formation is unknown. Of the many current theories, majority opinion probably favours a ‘supersaturation’ mechanism, in which the urine concentrations of the ions of a poorly soluble salt exceed the ‘precipitation product’ for that particular salt, thereby causing spontaneous nucleation and subsequent growth of salt crystals.
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MACGREGOR, J., NORDIN, B. & ROBERTSON, W. Solubility of Renal Stones. Nature 207, 861 (1965). https://doi.org/10.1038/207861a0
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DOI: https://doi.org/10.1038/207861a0
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