Letter | Published:

Changes of Histone Composition in the Developing Chick Embryo

Naturevolume 207pages638640 (1965) | Download Citation



THE possible role of histones as gene suppressors has been discussed by many authors1–5. If histones do have such a function, one might expect to find some qualitative or quantitative changes in the histone pattern during the course of development, reflecting steps in the processes of differentiation. However, up to now no conclusive evidence of this has been produced. Small changes have been demonstrated in the electrophoretic pattern of total nuclear histone from embryonic chick liver during development6.

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  1. Zoophysiological Institute, University of Lund, Sweden

    • I. P. S. AGRELL


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