Precocious Anti-diphtheria Response induced by RNA Immuno-carrier


IN previous papers an increase of the RNA content in the serum of rabbits immunized with horse serum albumin and rat or guinea-pig red blood cells was observed; the greatest increase was in the gamma-globulin fraction. The RNA extracted from immune rabbit sera (RNA Immuno-Carrier or RNA-I-C) was able to induce in normal rabbits a precocious antibody production against the same antigens used for immunizing the animals' source of the RNA1,2.

Access options

Rent or Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.


  1. 1

    Michelazzi, L., Nanni, G., and Baldini, I., as reported at the meeting of Soc. Ital. Biol. Sperim. (March, 1964).

  2. 2

    Michelazzi, L., Nanni, G., Baldini, I., and Novelli, A., Experientia, 20, 447 (1964).

  3. 3

    Michelazzi, L., Baldini, I., Novelli, A., and Nanni, G., Nature, 205, 194 (1965).

  4. 4

    Michelazzi, L., Novelli, A., Nanni, G., and Baldini, I., Experientia, 20, 703 (1964).

  5. 5

    Jensen, Cl., Acta Path. Microbiol. Scand., 10, 137 (1933).

  6. 6

    Spectors, W. S., Handbook of Biological Data (W. B. Saunders Co., Philadelphia, 1961).

Download references

Author information

Rights and permissions

Reprints and Permissions

About this article

Cite this article

MICHELAZZI, L., NANNI, G., BALDINI, I. et al. Precocious Anti-diphtheria Response induced by RNA Immuno-carrier. Nature 207, 1406–1408 (1965).

Download citation

Further reading


By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.