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Thermogenesis and Thyroid Action

Nature volume 204, pages 1311–1312 (1964)Cite this article

Abstract

FOB some time1,2 it has been realized that thyroid hormone raises metabolic rates, nincreases activity of the hexose monophosphate pathway, decreases apparent TPNH–DPN transhydrogenase activity and stimulates 5 α-steroid reductase activity. More recently thyroxin has been shown to increase by a factor of ten or twenty the activity of the intra-mitochondrial α-glycerophosphate dehydrogenase with no concurrent effect on the ‘soluble’ counterpart3,4.

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References

  1. Pitt-Rivers, R., and Tata, J. R., The Thyroid Hormones (Pergamon Press, New York, 1959).

    Google Scholar 

  2. Smith, R. E., and Hoijer, D., Physiol. Rev., 42, 60 (1962).

    Article  CAS  Google Scholar 

  3. Lee, Y.-P., Takemori, A. E., and Lardy, H. A., J. Biol. Chem., 234, 3051 (1959).

    CAS  PubMed  Google Scholar 

  4. Lardy, H. A., Lee, Y.-P., and Takemori, A. E., Ann. N.Y. Acad. Sci., 86, 506 (1960).

    Article  ADS  CAS  Google Scholar 

  5. Young, H. L., and Pace, N., Arch. Biochem. Biophys., 76, 112 (1958).

    Article  CAS  Google Scholar 

  6. Lehninger, A. C., Harvey Lectures, 49, 176 (1953–4).

    PubMed  Google Scholar 

  7. Hoch, E. L., and Lipman, F., Proc. U.S. Nat. Acad. Sci., 40, 909 (1954).

    Article  ADS  CAS  Google Scholar 

  8. Hannon, J. P., Rosenthal, A., and Durrer, J. L., Amer. J. Physiol., 204, 515 (1963).

    CAS  PubMed  Google Scholar 

  9. Reynafarje, B., and Chaffee, R. R. J., Proc. Soc. Exp Biol. and Med., 103, 225 (1960).

    Article  CAS  Google Scholar 

  10. Fairhurst, A., Roberts, J. C., and Smith, R. E., Amer. J. Physiol., 197, 370 (1959).

    CAS  PubMed  Google Scholar 

  11. Smith, R. E., Fed. Proc., 19, 64 (1960).

    CAS  Google Scholar 

  12. Tata, J. R., Ernster, L., Lindberg, O., Arrhenius, E., Pedersen, S., and Hedman, R., Biochem. J., 85, 408 (1963).

    Article  Google Scholar 

  13. Lynen, F., and Decker, K., Ergebn. de Physiol., 49, 327 (1957).

    Article  CAS  Google Scholar 

  14. Smith, R. E., Fed. Proc., 22, 738 (1963).

    CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Physiology, University of California, Los Angeles School of Medicine, Los Angeles, 24, California

    ROBERT E. SMITH

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  1. ROBERT E. SMITH
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SMITH, R. Thermogenesis and Thyroid Action. Nature 204, 1311–1312 (1964). https://doi.org/10.1038/2041311a0

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