Abstract
THE role of brown adipose tissue in thermoregulatory heat production of the cold-adapted rat was inferred by R. E. Smith from the thermogenic activity of the interscapular fat in vitro1 and the anatomical distribution of brown adipose tissue in the body2. The thermogenic role of brown fat has been directly demonstrated in the hibernating hamster by measuring temperatures at various sites in the body3, and by measuring simultaneously the oxygen consumption of the whole animal, in the new-born rabbit4,5.
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References
Smith, R. E., The Physiologist, 4, 113 (1961).
Smith, R. E., Fed. Proc., 21, 221 (1962).
Smith, R. E., and Hock, R. J., Science, 140, 199 (1963).
Dawkins, M. J. R., and Hull, D., J. Physiol. (Lond.), 169, 101 P (1963).
Dawes, G. S. (personal communication).
Donhoffer, Sz., Szegvári, Gy, Varga-Nagy, I., Járai, I., and Haug-László, A., Acta physiol. hung., 13, 37 (1957).
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DONHOFFER, S., SÁRDY, F. & SZEGVÁRI, G. Brown Adipose Tissue and Thermoregulatory Heat Production in the Rat. Nature 203, 765–766 (1964). https://doi.org/10.1038/203765b0
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DOI: https://doi.org/10.1038/203765b0
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