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Synthesis of Deoxyadenosine under Simulated Primitive Earth Conditions

Nature volume 203, pages 400–401 (1964)Cite this article

Abstract

RECENT experiments have demonstrated that many organic compounds of biological significance can be produced in a wide variety of experiments simulating primitive Earth conditions, The synthesis of the purines, adenine1,2 and guanine3, and the sugars, ribose4 and deoxyribose4,5, have been reported. It was therefore of interest to find out whether the nucleosides and nucleotides present in RNA and DNA could be synthesized under similar conditions.

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References

  1. Oro, J., and Kimball, A. P., Arch. Biochem. Biophys., 94, 217 (1961).

    Article  CAS  Google Scholar 

  2. Ponnamperuma, C., Lemmon, R. M., Mariner, R., and Calvin, M., Proc. U. S. Nat. Acad. Sci., 49, 737 (1963).

    Article  ADS  CAS  Google Scholar 

  3. Ponnamperuma, C., and Mariner, R., Nineteenth Intern. Cong. Pure and App. Chem., London (July 1963).

  4. Ponnamperuma, C., and Mariner, R., Rad. Res., 19, 183 (1963).

    Google Scholar 

  5. Oro, J., and Cox, A. C., Fed. Proc., 25, 80 (1962).

    Google Scholar 

  6. Ponnamperuma, C., Sagan, C., and Mariner, R., Nature, 199, 222 (1963).

    Article  ADS  CAS  Google Scholar 

  7. Ponnamperuma, C., Kirk, P., Tyson, B., and Mariner, R., Nature, 202, 393 (1964).

    Article  ADS  CAS  Google Scholar 

  8. Miller, S. L., Biochim. Biophys. Acta, 23, 480 (1957).

    Article  CAS  Google Scholar 

  9. Khorana, H. G., Some Recent Developments in the Chemistry of Phosphate Esters of Biological Interest (John Wiley and Sons, New York, 1963).

    Google Scholar 

  10. Ponnamperuma, C., and Kirk, P. (unpublished results).

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Authors and Affiliations

  1. Exobiology Division, National Aeronautics and Space Administration, Ames Research Center, Moffett Field, California

    CYRIL PONNAMPERUMA & PATRICIA KIRK

Authors
  1. CYRIL PONNAMPERUMA
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  2. PATRICIA KIRK
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PONNAMPERUMA, C., KIRK, P. Synthesis of Deoxyadenosine under Simulated Primitive Earth Conditions. Nature 203, 400–401 (1964). https://doi.org/10.1038/203400a0

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