Abstract
THE phenomenon known as ‘gene conversion’1, which results in the production of tetrads in which a pair of alleles segregates in a 3 : 1 ratio, instead of the usual 2 : 2 ratio, has been explained on the basis of a copy-choice theory2. Such an explanation is unacceptable unless the conservative replication of chromatids, at least in part, is also hypothesized3. It is generally accepted that both the DNA double helix4 and chromatids replicate semi-conservatively5. However, there exists evidence which suggests that the DNA double helix may replicate conservatively6.
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MARIMUTHU, K., THRELKELD, S. Tetrad Analysis by Autoradiography. Nature 203, 101–102 (1964). https://doi.org/10.1038/203101a0
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DOI: https://doi.org/10.1038/203101a0
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