Abstract
RIFAMYCINS are new antibiotics1,2 having a marked inhibitory effect on the growth of many Gram-positive bacteria, including staphylococci3,4, and have already been shown to affect bacterial respiration5. In this communication some results are reported concerning the effect of rifamycin SV and rifamycin M14 on the incorporation of amino-acids into protein by cell-free extracts of B. subtilis strain A.T.C.C. 6633.
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References
Sensi, P., Greco, A. M., and Ballotta, R., Antibiotics Annual, 262 (1959–60).
Sensi, P., Ballotta, R., and Gallo, G. G., Il Farmaco, 16, 165 (1961).
Sensi, P., Margalith, P., and Timbal, M. T., Il Farmaco, Sci. ed., 14, 146, (1959).
Furesz, S., and Scotti, R., Antibiotics Annual, 285 (1959–60).
In the press.
Bücher, T., and Pfleiderer, G., Methods in Enzymology, 1, 435 (Acad. Press, Inc., New York, 1955).
Tissières, A., Schlessinger, D., and Gros, F., Proc. U.S. Nat. Acad. Sci., 46, 1450 (1960).
Matthaei, H. J., and Nirenberg, M. W., Proc. U.S. Nat. Acad. Sci., 47, 1580 (1961).
Demoss, G. A., and Novelli, G. D., Biochim. Biophys. Acta, 22, 49 (1956).
Boman, H. G., and Svensson, I., Nature, 191, 674 (1961).
Berg, P., Bergmann, F. H., Ofengand, J., and Dieckman, H., J. Biol. Chem., 236, 1726 (1961).
Marmur, J., J. Mol. Biol., 3, 208 (1961).
Ofengand, J., and Haselkorn, R., Biochem. Biophys. Res. Commun., 6, 469 (1961–62).
Rendi, R., and Ochoa, S., J. Biol. Chem., 237, 3711 (1962).
Franklin, T. J., Biochem. J., 87, 449 (1963).
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FRONTALI, L., LEONI, L. & TECCE, G. Action of Rifamycin on Incorporation of Amino-acids into Protein in Cell-free Systems from B. subtilis. Nature 203, 84–85 (1964). https://doi.org/10.1038/203084b0
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DOI: https://doi.org/10.1038/203084b0
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