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Biochemical and Physiological Function of Thiamine in Nervous Tissue

Abstract

A CONSIDERABLE amount of evidence has been accumulated, primarily as a result of studies by von Muralt et al.1, to suggest that thiamine may play a vital part in peripheral neurophysiology that is independent of its classical role as a coenzyme. Experiments in our laboratory suggest that thiamine may function as a neurohumour in the central nervous system, and, in addition, may be involved with sodium transport.

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COOPER, J., ROTH, R. & KINI, M. Biochemical and Physiological Function of Thiamine in Nervous Tissue. Nature 199, 609–610 (1963). https://doi.org/10.1038/199609a0

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