Abstract
IN order to investigate the non-specific stimulation of the reticulo-endothelial system and consequences of this stimulation on the intensity of specific immune reactions it was decided to find out whether bacillus Calmette-Guérin (B.C.G.) infection would influence the rate and intensity of homograft reaction. Results have already shown1 that the first set homograft rejection was markedly accelerated in B.C.G. infected rats. A similar effect was described by Balner, Old and Clarke2. They observed an accelerated skin graft rejection in B.C.G. infected female C57BL/6 mice grafted with isologous male skin.
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References
Vitale, B., and Allegretti, N., Abstr. Comm., Second Yugoslav Cong. Biol., Belgrade, 125 (1962).
Balner, H., Old, L. J., and Clarke, D. A., Proc. Soc. Exp. Biol. and Med., 109, 58 (1962).
Bailey, D. W., and Usama, B., Transplant. Bull., 7, 429 (1960).
Berrian, J. H., and McKhann, C. F., Ann. N.Y. Acad. Sci., 87, 106 (1960).
Zaalberg, O. B., Biological Problems of Grafting, 306 (Université de Liège, 1959).
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VITALE, B., ALLEGRETTI, N. Influence of Bacillus Calmette-Guérin Infection on the Intensity of Homograft Reaction in Rats. Nature 199, 507–508 (1963). https://doi.org/10.1038/199507a0
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DOI: https://doi.org/10.1038/199507a0
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