Abstract
SEVERAL viruses of the papovavirus group, namely, polyoma, SV–40, and rabbit papilloma viruses, produce hereditable morphological alterations—‘transformation’ —of appropriate tissue culture cells1. We have found that another member of this group, the bovine papilloma virus, produces cellular alterations and proliferation in certain bovine tissue culture cells after a very short latent period.
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References
Vogt, M., and Dulbecco, R., Proc. U.S. Nat. Acad. Sci., 46, 365 (1960). Koprowski, H., Ponten, J. A., Jensen, F., Ravdin, R. G., Moorhead, P., and Saksela, E., J. Cell Comp. Physiol., 59, 281 (1962). Shein, H. M., and Enders, J. F., Proc. U. S. Nat. Acad. Sci., 48, 1164 (1962). Coman, D. R., Cancer Res., 6, 602 (1946). De Maeyer, E., Science, 136, 985 (1962).
McQuilkin, W. T., Evans, V. J., and Earle, W. R., J. Nat. Cancer Inst., 19, 885 (1957).
Huebner, R. J., Lane, W. T., and Reynolds, J. G. (in preparation).
Segre, D., Olson, jun., C., and Hoerlein, A. B., Amer. J. Vet. Res., 16, 517 (1955).
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BLACK, P., HARTLEY, J., ROWE, W. et al. Transformation of Bovine Tissue Culture Cells by Bovine Papilloma Virus. Nature 199, 1016–1018 (1963). https://doi.org/10.1038/1991016a0
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DOI: https://doi.org/10.1038/1991016a0
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