Abstract
EVIDENCE that the concentration of calcium in the blood directly controls parathyroid activity has been obtained in whole animals1,2. Gaillard3 found that parathyroid glands could be maintained in organ cultures and that the medium in which these glands had been cultivated could stimulate bone resorption. These findings prompted me to examine the effect of changes in calcium concentration in the medium on parathyroid growth and secretion in vitro.
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References
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Copp, H. D., and Davidson, G. F., Proc. Soc. Exp. Biol. and Med., 107, 342 (1961).
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Biggers, J. D., Gwatkin, R. B. L., and Heyner, S., Exp. Cell. Res., 25, 41 (1961).
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Raisz, L. G., Nature, 197, 1015 (1963).
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RAISZ, L. Regulation by Calcium of Parathyroid Growth and Secretion in vitro. Nature 197, 1115–1116 (1963). https://doi.org/10.1038/1971115a0
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DOI: https://doi.org/10.1038/1971115a0
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