Abstract
BASE ratios can be determined with microelectrophoresis (microphoresis) in as little as 5 × 10−10 g RNA1, a sensitivity which permits intracellular analysis in suitable material. It would be of interest for turn-over studies to evaluate radioactivity in the separated RNA components. Autoradiography is the simplest tool for this purpose, both because of its sensitivity and high resolution.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Edström, J.-E., J. Biophys. Biochem. Cytol., 8, 39 (1960).
Sirlin, J. L., Kato, K.-I., and Jones, K. W., Biochim. Biophys. Acta, 48, 421 (1961).
Edström, J.-E., Grampp, W., and Schor, N., J. Biophys. Biochem. Cytol., 11, 549 (1961).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
SIRLIN, J., EDSTRÖM, JE. A Combined Microphoresis-Autoradiography Technique. Nature 197, 89–90 (1963). https://doi.org/10.1038/197089a0
Issue Date:
DOI: https://doi.org/10.1038/197089a0
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
