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Influence of Ionizing Radiation on Glutaminase Activity in Mouse Brain and Liver

Abstract

IN 1940, Dale1 demonstrated that carboxypeptidase activity is inhibited if submitted to small doses of X-rays. Bekkum2, Potter3 and Nadson4 showed that under ionizing radiations primary changes occur in the mitochondria. We have investigated the variations of the in vivo behaviour of glutaminase activity in liver and brain of mice submitted to an overall 58-min irradiation with 500 r.

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References

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  2. Van Bekkum, D. W., Ciba Found. Symp. Ionizing Radiation and Cell Metabolism, 77 (London, 1956).

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  3. Potter, R. L., and Bethel, F. N., Fed. Proc., 11, 270 (1952).

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  4. Nadson, G. A., and Rochlin, E. J., Protoplasma, 20, 31 (1934).

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ABABEI, L., SCHIAU, S., CǍPÎLN, S. et al. Influence of Ionizing Radiation on Glutaminase Activity in Mouse Brain and Liver. Nature 196, 1223–1224 (1962). https://doi.org/10.1038/1961223a0

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  • DOI: https://doi.org/10.1038/1961223a0

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