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Release of Peroxidase from Eosinophil Granules in vitro

Abstract

THE eosinophil is a phagocytic cell1, and following the ingestion by eosinophils of sensitized red cells many of the eosinophil granules disappear2. Histochemical studies recently have shown that eosinophil granules contain significant amounts of the enzyme peroxidase3. The conditions necessary for lysis of the granules and release of peroxidase were investigated in the present work, using preparations of eosinophils isolated from the peritoneal cavity of the rat.

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References

  1. Mesnil, M. A., quoted by Vaughan, J., Blood, 8, 1 (1953).

    Google Scholar 

  2. Archer, G. T., and Bosworth, N., Austral. J. Exp. Biol., 39, 157 (1961).

    Article  CAS  Google Scholar 

  3. Rytömaa, T., Acta Path. Microbiol. Scand., 50, Supp. 140, 79 (1960).

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  4. Bosworth, N., and Archer, G. T., Austral. J. Exp. Biol., 39, 165 (1961).

    Article  Google Scholar 

  5. Jermyn, M. A., and Thomas, R., Biochem. J., 56, 631 (1954).

    Article  CAS  Google Scholar 

  6. Hirsch, J. G., and Cohn, Z. A., J. Exp. Med., 112, 1005 (1960).

    Article  CAS  Google Scholar 

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ARCHER, G. Release of Peroxidase from Eosinophil Granules in vitro. Nature 194, 973–974 (1962). https://doi.org/10.1038/194973b0

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